Definitions for opsonisation
op·son·i·sa·tion

Princeton's WordNetRate this definition:0.0 / 0 votes

1. opsonization, opsonisationnoun

   process whereby opsonins make an invading microorganism more susceptible to phagocytosis

WikipediaRate this definition:0.0 / 0 votes

1. opsonisation

   Opsonins are extracellular proteins that, when bound to substances or cells, induce phagocytes to phagocytose the substances or cells with the opsonins bound. Thus, opsonins act as tags to label things in the body that should be phagocytosed (i.e. eaten) by phagocytes (cells that specialise in phagocytosis, i.e. cellular eating). Different types of things ("targets") can be tagged by opsonins for phagocytosis, including: pathogens (such as bacteria), cancer cells, aged cells, dead or dying cells (such as apoptotic cells), excess synapses, or protein aggregates (such as amyloid plaques). Opsonins help clear pathogens, as well as dead, dying and diseased cells.Opsonins were discovered and named "opsonins" in 1904 by Wright and Douglas, who found that incubating bacteria with blood plasma enabled phagocytes to phagocytose (and thereby destroy) the bacteria. They concluded that: “We have here conclusive proof that the blood fluids modify the bacteria in a manner which renders them a ready prey to the phagocytes. We may speak of this as an “opsonic” effect (opsono - I cater for; I prepare victuals for), and we may employ the term “opsonins” to designate the elements in the blood fluids which produce this effect.”Subsequent research found two main types of opsonin in blood that opsonised bacteria: complement proteins and antibodies. However, there are now known to be at least 50 proteins that act as opsonins for pathogens or other targets.

ChatGPTRate this definition:0.0 / 0 votes

1. opsonisation

   Opsonisation is the process by which pathogens, such as bacteria or viruses, are marked for destruction by the immune system. This is typically achieved by coating the pathogen with specific molecules called opsonins, which can be recognized and bound to by immune cells. The binding process enhances phagocytosis, a mechanism by which immune cells engulf and destroy the marked pathogens. Thus, opsonisation increases the efficiency of the immune response.

Matched Categories

1. • Bodily Process

How to pronounce opsonisation?

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Numerology

1. Chaldean Numerology

   The numerical value of opsonisation in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of opsonisation in Pythagorean Numerology is: 4

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=opsonisation
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Opsonisation
3. ^ ChatGPT
   https://chat.openai.com